Search on: NECROSIS FACTORS, TUMOR 
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Descriptor English:   Tumor Necrosis Factors 
Descriptor Spanish:   Factores de Necrosis Tumoral 
Descriptor Portuguese:   Fatores de Necrose Tumoral 
Synonyms English:   TNF Receptor Ligands
Tumor Necrosis Factor Superfamily Ligands
Necrosis Factors, Tumor
Receptor Ligands, TNF  
Tree Number:   D12.644.276.374.750
D12.776.467.374.750
D23.529.374.750
Definition English:   A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS. 
History Note English:   2005 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   38737 
Unique Identifier:   D048069 

Occurrence in VHL:
 

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